癌变·畸变·突变 ›› 1998, Vol. 10 ›› Issue (1): 1-004.doi: 10.3969/j.issn.1004-616x.1998.01.002

• 论著 • 上一篇    下一篇

阻遏诱变剂镉在海洋生物中传递的物质及作用机理的研究( Ⅲ) 海参提取液

林光恒 刘明星 孙国琼   

  1. 中国科学院海洋研究所 青岛266071
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:1998-01-30 发布日期:1998-01-30

STUDY OF THE PROHIBITOR AGAINST TRANSFER OF Cd2 + —MUTAGEN IN MARINE ORGANISMS AND ITS MECHANISM Ⅲ.SEA - CUCUMBER ABSTRACT

Lin Guangheng , Liu Mingxing , Sun Guoqiong   

  1. Instit ute of Oceanology , Chinese Academy of Sciences , Qingdao 266071
  • Received:1900-01-01 Revised:1900-01-01 Online:1998-01-30 Published:1998-01-30

摘要: 海参是我国民间食疗的重要补品,具健体壮阳之功效。海参皂甙(Holothurin) 是海参水提取物的主要成分。本文报道了海参水提取物在中国对虾( Penaeus orientalis) 体内具有阻遏诱变剂镉被对虾肌体吸收和积累的作用,经化学分析和遗传毒性分析均一致证明该提取物是诱变剂镉的有效阻遏剂或抑制剂,能有效地提高对虾机体抗毒性作用。

关键词: 海参提取液, 镉, 诱发剂, 中国对虾, 紫露草四分体微核分析

Abstract: Sea2cucumber is rich in nut rient s which has been considered by Chinese to be a nourishing sea2food. It has the efficacy in nourishing the kidney and st rengthening the human body.Holothurin is the main constituent in sea2cucumber abst ract with water. Present paper reports its activity of prohibiting Cd2 +2mutagen to be absorbed and accumulated by the prawn body ( Penaeus orientalis) and decreasing it s genotoxicity. All those were verified by chemical analysis with PRGP and mutagenic test with Trad2MCN.

Key words: Sea2cucumber abst ract, Cadmium, Mutagen, Penaeus orientalis, Trad2MCN test